Simulation: the new Scaling Law — Joon Sung Park, Simile AI
Simile’s CEO about his journey from the viral Generative Agents to creating 8 Billion Digital Twins of every living human... and why it’s gone from fun exploration to very serious business.
🔬The BioAI Phase Shift - Matthew McPartlon & Neil Patil, Chai Discovery
Pharma is suddenly paying for Bio × AI tools, and Chai is leading the pack with four deals closed this summer. Cofounder Matt McPartlon and Product leader Neil Patil explain why.
The Inference Engineering Masterclass — Philip Kiely & Ali Taha, Baseten
Baseten just raised a $13B Series F and is now one of the leading kings of inference engineering. We go into everything you need to know for autoregressive and diffusion engineering.
Codex from 0 to 10M Users: Building ChatGPT Work — Akshay Nathan, OpenAI
OpenAI's core product engineering lead on how they are building ChatGPT Work to make AGI accessible to all of humanity: Sites, OpenClaw, Memory, Subagents, Finance, No-Code and advice.
Poolside's co-CEO on how his small team of top researchers built a model factory capable of training Laguna S - a 118B MOE beating Thinky's ~1T open weights model... and this is just the beginning.
🔬 The Lab of the Future Should Feel Like a Data Center — Andy Beam & Rafa Gómez-Bombarelli, Lila Sciences
Lila is betting that science, not the internet, is the last untapped source of training data. We went to find out what that actually looks like in a room full of robots.
Why AI Infrastructure must evolve for Agent Experience — Akshat Bubna, Modal CTO
2 years after our first coverage, we return with Modal's other cofounder to explore why Agent Experience is working now, and everything they have learned building the new agent cloud.
🔬 The Coolest Diffusion Research Isn't in LLMs — Evan Feinberg & Sergey Edunov, Genesis Molecular AI
Why the Llama lead left Meta for drug discovery, PEARL's zero-shot OpenBind win, and what becomes possible when co-folding finally crosses the accuracy threshold.
The Professor of Outputmaxxing — Anjney Midha, AMP
We talk about how this legendary investor went from humble beginnings in Singapore to leading rounds in Anthropic, Mistral, Black Forest Labs, and Periodic Labs... and the AMP secret master plan!
GitHub pioneered the modern AI coding era with Copilot, and the resulting explosion in agentic coding has led to notable strains on the most popular developer platform in the world. Here's the plan.
Why Video Agent models are next — Ethan He, xAI Grok Imagine
Inside xAI: Building Grok Imagine in 3 Months, Videogen vs World Models, and why Grok Imagine is so underrated. For the first time, we do a deep dive with the guy who led it!
The Autonomous Drone Tech Stack & Economics of Drones — Yaroslav Azhnyuk, The Fourth Law & Guest Host Noah Smith, Noahpinion
Ukrainian drone founder Yaroslav Azhnyuk went from pet cameras to AI-guided weapons. He and guest host Noah Smith make the case that the West is asleep at the wheel.
